What is Peyronie's Disease?
Peyronie's Disease, also know as Induratio Penis Plastica (IPP), is a disorder involving areas of inflammation followed by fibrosis (scarring) along the shaft of the penis. There may be a single lesion or multiple lesions, known as plaque, that are located below the surface of the skin. Plaque has the appearance and feel of a hardened flat disk.

Peyronies's Disease does not cause major health problems and is not life threatening but is distressing to many individuals. Frequently there is pain, angulation (bending) of the penis, and difficulty with erections and sexual relations. The natural history of the disease is not encouraging. In some men, the plaque may become smaller in size and disappear completely. however, the majority of men with Peyronie's Disease experience intermittent flare-ups and eventual calcification (hardening) of the plaque. The chalky bone-like plaque then becomes a permanent part of the penis.